Mouse CD20 expression and function

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Mouse CD20 expression and function.

CD20 plays a role in human B cell proliferation and is an effective target for immunotherapy. In this study, mouse CD20 expression and biochemistry were assessed for the first time using a new panel of CD20-specific mAb, with CD20 function assessed using CD20-deficient (CD20(-/-)) mice. CD20 expression was B cell restricted and was initiated during late pre-B cell development. The frequency and...

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ژورنال

عنوان ژورنال: International Immunology

سال: 2004

ISSN: 1460-2377

DOI: 10.1093/intimm/dxh009